Cancer-Causing Radiation Biggest Threat to Humans on Deep Space Missions
by Staff Writers
Washington (Sputnik) Mar 13, 2017
Researchers looking into the effects of deep space travel on the human body may have just discovered something that could jeopardize humankind's chances of a successfully colonizing Mars. With work currently underway by major space agencies such as NASA to send a manned mission to Mars, the potential for space exploration has deepened.
Yet now, even before the first human has gone beyond the moon, some potentially life-threatening problems have been discovered that could dash hopes of establishing a colony on the Red Planet. New research carried out by the Wake Forest Institute for Regenerative Medicine, has been looking at the potential effects of deep space radiation on the human body.
Using mice transplanted with human stem cells, the study has shown that there was a notable increase in the appearance of leukaemia cells when the subjects were exposed to the same level of radiation that would be experienced by astronauts who would travel to Mars.
A constant bombardment of this radiation would have astronauts sick before they even arrived after the three-year journey.
?The findings, which were published in the journal Leukemia, were "troubling," according to Christopher Porada, an associate professor of regenerative medicine and a senior researcher on the project.
The research, which was sponsored by NASA, proved that space travel could pose some serious health risks.
"Our results are troubling because they show radiation exposure could potentially increase the risk of leukemia in two ways," Professor Porada said.
"It is rewarding to use our expertise in stem cells to help NASA evaluate the potential health risks of space travel and hopefully develop strategies to address them," he added.
The goal of the research was to look at the effects of simulated solar energetic particles (SEP) and galactic cosmic ray (GCR) radiation on human hematopoietic stem cells (HSCs). There is less than 0.1 percent of the bone marrow in adults within these stem cells, but they produce many types of blood cells that circulate throughout the body and work to transport oxygen as well as fight infection.
The researchers exposed human HCSs from healthy donors to radiation that astronauts would be exposed to in deep space at the NASA Space Radiation Laboratory and Brookhaven National Laboratory.
Wake Forest Institute for Regenerative Medicine scientists then performed lab and animal studies to define the impact of the exposure.
They found that the levels of exposure dramatically affected the health and function of the HSCs.
"Radiation exposure at these levels was highly deleterious to HSC function, reducing their ability to produce almost all types of blood cells, often by 60-80 percent," Professor Porada said.
"This could translate into a severely weakened immune system and anemia during prolonged missions in deep space," he added.
Mr. Porada said that the results have shown that radiation exposure could potentially increase the risk of leukemia in two ways.
"We found that genetic damage to HSCs directly led to leukemia. Secondly, radiation also altered the ability of HSCs to generate T and B cells, types of white blood cells involved in fighting foreign 'invaders' like infections or tumor cells. This may reduce the ability of the astronaut's immune system to eliminate malignant cells that arise as a result of radiation-induced mutations."
The researchers have said that they will continue to look at this work and will also aim to establish how they can make space travel as safe as possible for all concerned.
Source: Sputnik News
Greenbelt MD (SPX) Mar 03, 2017
Our constantly-changing sun sometimes erupts with bursts of light, solar material, or ultra-fast energized particles - collectively, these events contribute to space weather. In a study published Jan. 30, 2017, in Space Weather, scientists from NASA and the National Center for Atmospheric Research, or NCAR, in Boulder, Colorado, have shown that the warning signs of one type of space weather even ... read more
Wake Forest Institute for Regenerative Medicine
Space Technology News - Applications and Research
|The content herein, unless otherwise known to be public domain, are Copyright 1995-2024 - Space Media Network. All websites are published in Australia and are solely subject to Australian law and governed by Fair Use principals for news reporting and research purposes. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA news reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. All articles labeled "by Staff Writers" include reports supplied to Space Media Network by industry news wires, PR agencies, corporate press officers and the like. Such articles are individually curated and edited by Space Media Network staff on the basis of the report's information value to our industry and professional readership. Advertising does not imply endorsement, agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. General Data Protection Regulation (GDPR) Statement Our advertisers use various cookies and the like to deliver the best ad banner available at one time. All network advertising suppliers have GDPR policies (Legitimate Interest) that conform with EU regulations for data collection. By using our websites you consent to cookie based advertising. If you do not agree with this then you must stop using the websites from May 25, 2018. Privacy Statement. Additional information can be found here at About Us.|