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World's smallest wearable device warns of UV exposure, enables precision phototherapy by Staff Writers Chicago IL (SPX) Dec 06, 2018
The world's smallest wearable, battery-free device has been developed by Northwestern Medicine and Northwestern's McCormick School of Engineering scientists to measure exposure to light across multiple wavelengths, from the ultra violet (UV), to visible and even infrared parts of the solar spectrum. It can record up to three separate wavelengths of light at one time. The device's underlying physics, and extensions of the platform to a broad array clinical applications are reported in this study to be published Dec. 5 in Science Translational Medicine. These foundational concepts form the basis of consumer devices launched in November to alert consumers to their UVA exposure, enabling them to take action to protect their skin from sun damage. When the solar-powered, virtually indestructible device was mounted on human study participants, it recorded multiple forms of light exposure during outdoor activities, even in the water. The device monitored therapeutic UV light in clinical phototherapy booths for psoriasis and atopic dermatitis as well as blue light phototherapy for newborns with jaundice in the neonatal intensive care unit. It also demonstrated the ability to measure white light exposure for seasonal affective disorder. As such, it enables precision phototherapy for these health conditions, and it can monitor, separately and accurately, UVB and UVA exposure for people at high risk for melanoma, a deadly form of skin cancer. For recreational users, the sensor can help warn of impending sunburn. The device was designed by a team of researchers in the group of John Rogers, the Louis Simpson and Kimberly Querrey Professor of Materials Science and Engineering, Biomedical Engineering in the McCormick School of Engineering and a professor of neurological surgery at Northwestern's Feinberg School of Medicine. "From the standpoint of the user, it couldn't be easier to use - it's always on yet never needs to be recharged," Rogers said. "It weighs as much as a raindrop, has a diameter smaller than that of an M and M and the thickness of a credit card. You can mount it on your hat or glue it to your sunglasses or watch." It's also rugged, waterproof and doesn't need a battery. "There are no switches or interfaces to wear out, and it is completely sealed in a thin layer of transparent plastic," Rogers said. "It interacts wirelessly with your phone. We think that it will last forever." Rogers tried to break it. His students dunked devices in boiling water and in a simulated washing machine. They still worked. Northwestern scientists are particularly excited about the device's use for measuring the entire UV spectrum and accumulating total daily exposure. "There is a critical need for technologies that can accurately measure and promote safe UV exposure at a personalized level in natural environments," said co-senior author Dr. Steve Xu, instructor in dermatology at Feinberg and a Northwestern Medicine dermatologist. "We hope people with information about their UV exposure will develop healthier habits when out in the sun," Xu said. "UV light is ubiquitous and carcinogenic. Skin cancer is the most common type of cancer worldwide. Right now, people don't know how much UV light they are actually getting. This device helps you maintain an awareness and for skin cancer survivors, could also keep their dermatologists informed." Light wavelengths interact with the skin and body in different ways, the scientists said. "Being able to split out and separately measure exposure to different wavelengths of light is really important," Rogers said. "UVB is the shortest wavelength and the most dangerous in terms of developing cancer. A single photon of UVB light is 1,000 times more erythrogenic, or redness inducing, compared to a single photon of UVA." In addition, the intensity of the biological effect of light changes constantly depending on weather patterns, time and space. "If you're out in the sun at noon in the Caribbean, that sunlight energy is very different than noon on the same day in Chicago," Xu said. Skin cancer is reaching epidemic proportions in the U.S. Basal cell carcinoma and squamous cell carcinoma of the skin account for more than 5.4 million cases per year at a cost of $8.1 billion dollars yearly. In 2018, there will be an estimated 178,000 new cases of melanoma, causing 9,000 deaths. Every hour, one person dies of melanoma.
First accurate dosing of phototherapy Because the device operates in an "always on" mode, its measurements are more precise and accurate than any other light dosimeter now available, the scientists said. Current dosimeters only sample light intensity briefly at set time intervals and assume that the light intensity at times between those measurements is constant, which is not necessarily the case, especially in active, outdoor use scenarios. They are also clunky, heavy and expensive.
How the tiny sensor works Multiple detectors and capacitors allow measurements of UVB and UVA exposure separately. The device communicates with the users' phone to access weather and global UV index information (the amount of light coming through the clouds). By combining this information, the user can infer how much time they have been in the direct sun and out of shade. The user's phone can then send an alert if they have been in the sun too long and need to duck into the shade.
ESA team blasts Intel's new AI chip with radiation at CERN Paris (ESA) Dec 04, 2018 An ESA-led team subjected Intel's new Myriad 2 artificial intelligence chip to one of the most energetic radiation beams available on Earth. This test of its suitability to fly in space took place at CERN, the European Organization for Nuclear Research. The AI chip is related in turn to an ESA-fostered family of integrated circuits. The Myriad 2 harnesses artificial intelligence for high-performance, low-power vision processing. It can be pre-trained with data to recognise particular features and ... read more
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