. 24/7 Space News .
Space Station Shrinks Fluorescence Microscopy Tool
by Melissa Gaskill for ISS Science News
Houston TX (SPX) Jul 11, 2018

Image of fixed macrophages using three chromophores created by the FLUMIAS-DEA miniaturized fluorescence microscope during Science Verification Test.

Honey, I shrunk the microscope! A miniaturized fluorescence microscope makes it possible to observe changes in living cells in microgravity. Future observations of astronauts' cells could tell scientists important information about how the body adapts to space.

"An astronaut's physiology changes during long duration spaceflight because of the lack of gravity," said Principal Investigator Oliver Ullrich, University of Magdeburg.

"Knowing the molecular basis of this cellular response to altered gravity is key for risk management, monitoring, and development of countermeasures for future long-term space exploration.

"Cellular adaptation to the microgravity environment can only be studied and understood in dynamic or live measurements. Live imaging experiments in space are a crucial contribution to the understanding of cellular adaptation to microgravity."

An investigation aboard the International Space Station will demonstrate this new technology. FLUMIAS-DEA observes samples of fixed cells and live cells using a modified, patented illumination technique that contributes to the microscope's smaller size and reduced technical complexity.

"The dimensions of FLUMIAS-DEA can be accommodated in the volume of seven cubes inside the Space Tango TangoLab," said investigator Rainer Treichel of Airbus Defence and Space, which operates the investigation for the German Space Agency (DLR).

"At the beginning of its development, it was not clear whether this could be accomplished. Standard laboratory microscopes with comparable capabilities typically take up the space of a full-sized writing desk."

Fluorescence microscopy is a key tool in biological and medical science, used to visualize the spatial structure of cells and tissues. The technique applies an array of fluorochromes, or stains that respond to different wavelengths of irradiated light, to a specimen. The fluorescence microscope then irradiates the specimen with specific wavelengths to separate the signals of the stains.

This makes it possible to identify specific cells and sub-microscopic cellular components. Using fluorescence microscopy to observe living cells provides insights into dynamic cellular processes such as the transport of proteins within and between cells, cytoskeleton rearrangement, and ion flux, such as the flow of calcium ions into and out of a cell. High-resolution microscopes document these processes over time and in 3D.

This tool for 3D imaging of biological samples has many applications for research on the space station.

The FLUMIAS-DEA investigation is meant to pave the way for the use of fluorescence microscopy for more complex biological studies in space. A next-generation facility, called FLUMIAS-ISS, is currently in development for potential flight as early as 2020. It will enable investigation of inner cellular processes of mammalian and plant cells under variable artificial gravity levels between microgravity and 1 g.

A compact fluorescence microscope capable of providing 3D imaging of biological samples has potential applications on Earth, making it possible to use this valuable technology in remote environments and disaster situations.

This microscope might have shrunk, but there is nothing small about its potential.

Related Links
Space Tango TangoLab
Space Tourism, Space Transport and Space Exploration News

Thanks for being there;
We need your help. The SpaceDaily news network continues to grow but revenues have never been harder to maintain.

With the rise of Ad Blockers, and Facebook - our traditional revenue sources via quality network advertising continues to decline. And unlike so many other news sites, we don't have a paywall - with those annoying usernames and passwords.

Our news coverage takes time and effort to publish 365 days a year.

If you find our news sites informative and useful then please consider becoming a regular supporter or for now make a one off contribution.
SpaceDaily Monthly Supporter
$5+ Billed Monthly

paypal only
SpaceDaily Contributor
$5 Billed Once

credit card or paypal

Russian cargo ship docks at ISS in record time
Moscow (AFP) July 10, 2018
A Russian cargo vessel took just three hours and 40 minutes to reach the International Space Station on Tuesday, Roscosmos space agency said, smashing the record flight time by two hours. The "Progress" launched at 2151 GMT on Monday from the Baikonur Cosmodrome in Kazakhstan and arrived at the space station in the early hours of Tuesday, the agency said. "The length of the flight, between departure to its docking at the station, was three hours 40 minutes," the agency said in a statement, ad ... read more

Comment using your Disqus, Facebook, Google or Twitter login.

Share this article via these popular social media networks
del.icio.usdel.icio.us DiggDigg RedditReddit GoogleGoogle

Orion Jettison Motor Ready for Crew Escape System Test

Testing Refines Requirements for Deep Space Habitat Design

Making oxygen from water may pave way for long-distance space travel

NASA and Peanuts Worldwide to Collaborate on Deep Space Learning Activities

Experimental Spaceplane Program Successfully Completes Engine Test Series

Aurora Launch Services established in Alaska To provide responsive launch services

Largest-ever solid rocket motor poised for first hot firing

Chinese Space Company Planning Launch of Largest Privately Owned Liquid Rocket

Scientists Discover "Ghost Dunes" On Mars

UK space sector set to benefit from new European Space Agency contract

Airbus wins two ESA studies for Mars Sample Return mission

NASA listens out for Opportunity everyday

China readying for space station era: Yang Liwei

China launches new space science program

China Rising as Major Space Power

China launches new-tech experiment twin satellites

EIB and ESA to cooperate on increasing investments in the European Space Sector

China Mulls Creation of Joint Global Satellite System with Russia

Laser-Based System is Set to Expand Space-to-Ground Communication

Yes we've got a space agency - but our industry needs 'Space Prize Australia'

Astronomer Reveals When Soviet-Era Interplanetary Station Will Crash to Earth

Giant Satellite Fuel Tank Sets New Record for 3-D Printed Space Parts

New insights bolster Einstein's idea about how heat moves through solids

Spectral cloaking could make objects invisible under realistic conditions

NASA's Webb Space Telescope to Inspect Atmospheres of Gas Giant Exoplanets

TESS Spacecraft Continues Testing Prior to First Observations

NASA's Kepler Spacecraft Pauses Science Observations to Download Science Data

Rocky planet neighbor looks familiar, but is not Earth's twin

First Global Maps of Pluto and Charon from New Horizons Published

Europa's Ocean Ascending

Jupiter's moons create uniquely patterned aurora on the gas giant planet

'Cataclysmic' collision shaped Uranus' evolution

The content herein, unless otherwise known to be public domain, are Copyright 1995-2024 - Space Media Network. All websites are published in Australia and are solely subject to Australian law and governed by Fair Use principals for news reporting and research purposes. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA news reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. All articles labeled "by Staff Writers" include reports supplied to Space Media Network by industry news wires, PR agencies, corporate press officers and the like. Such articles are individually curated and edited by Space Media Network staff on the basis of the report's information value to our industry and professional readership. Advertising does not imply endorsement, agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. General Data Protection Regulation (GDPR) Statement Our advertisers use various cookies and the like to deliver the best ad banner available at one time. All network advertising suppliers have GDPR policies (Legitimate Interest) that conform with EU regulations for data collection. By using our websites you consent to cookie based advertising. If you do not agree with this then you must stop using the websites from May 25, 2018. Privacy Statement. Additional information can be found here at About Us.