NSF and CASIS Announce 4th Annual Solicitation in Tissue Engineering and Mechanobiology to utilize ISS

The Center for the Advancement of Science in Space (CASIS) and the National Science Foundation (NSF) announced their fourth annual joint solicitation for investigators to leverage the International Space Station (ISS) for research in the fields of tissue engineering and mechanobiology.

Up to $1.6 million will be awarded for multiple research investigations to support flight projects under the sponsorship of the ISS U.S. National Laboratory. An additional $450,000 may be available to support hardware and Implementation Partner costs for each awarded proposal. CASIS is the nonprofit responsible for management of the ISS National Lab through a Cooperative Agreement with NASA.

The purpose of this solicitation is to attract proposals that make use of the ISS National Lab for research projects in the fields of tissue engineering and mechanobiology. Responsive proposals will describe how the proposed research will utilize the ISS National Lab and its unique environment to develop novel ideas in either fundamental or translational research programs that integrate engineering and life sciences.

This solicitation comes on the heels of a recent announcement wherein three projects were selected by NSF to leverage the ISS National Lab for tissue engineering and mechanobiology research as a result of the 2019 solicitation.

Microgravity affects organisms-from viruses and bacteria to humans, inducing changes such as altered gene expression and DNA regulation, changes in cellular function and physiology, and 3D aggregation of cells. Spaceflight is advancing research in the areas of pharmaceutical development, disease modeling, regenerative medicine, and many other areas within the life sciences.

Through this partnership, CASIS will facilitate hardware implementation and in-orbit access to the ISS National Lab, and NSF will fund the selected projects to advance fundamental science and biomedical engineering knowledge. NSF supports transformative research to help drive the U.S. economy, enhance national security, and maintain America's position as a global leader in innovation.

Fundamental science and government agency sponsored research is an important line of business for the ISS National Lab, and knowledge gained from such research could have profound impacts on future inquiries that bring value to our nation and drive a sustainable and scalable market in low Earth orbit.

Prior to submitting a full proposal to NSF for this solicitation, all interested parties are requested to submit a Feasibility Review Form to the ISS National Lab for an evaluation on the operational feasibility of the proposed work to be conducted on the orbiting laboratory.

The deadline to submit a Feasibility Review Form is January 4, 2021. Only projects that pass the ISS National Lab Feasibility Review will be invited to submit a full proposal to NSF. The notification of a passing score must be included in the full proposal submission. NSF will close this grant solicitation on March 1, 2021.

ISS National Lab Tissue Engineering And Mechanobiology Science Annual Solicitation

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Dartmouth to conduct ISS research with NSF grant
Hanover NH (SPX) Nov 12, 2020
Dartmouth Engineering Professor Zi Chen has received a $400,000 grant from the National Science Foundation (NSF), in partnership with the Center for the Advancement of Science in Space (CASIS), to lead a three-year research project on the International Space Station (ISS). Chen's proposal was one of just three selected from institutions across the country as part of the NSF/CASIS solicitation to further knowledge of tissue engineering and mechanobiology utilizing the ISS. With the funding fo ... read more