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Chimp Genome Assembled: Draft Sequence Aligned With Human Genome
The National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), today announced the first draft version of the genome sequence of the chimpanzee and its alignment with the human genome. All of the data have been deposited into free public databases and are now available for use by scientists around the world. The sequence of the chimpanzee, Pan troglodytes, was assembled by NHGRI-funded teams led by Eric Lander, Ph.D., at The Eli & Edythe L. Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Mass.; and Richard K. Wilson, Ph.D., at the Genome Sequencing Center, Washington University School of Medicine, Saint Louis. Researchers deposited the initial assembly, which is based on four-fold sequence coverage of the chimp genome, into the NIH-run, public database, GenBank,. In turn, Genbank will distribute the sequence data to the European Molecular Biology Laboratory's Nucleotide Sequence Database, EMBL-Bank, and the DNA Data Bank of Japan, DDBJ. To facilitate biomedical studies comparing regions of the chimp genome with similar regions of the human genome, the researchers also have aligned the draft version of the chimp sequence with the human sequence. Those alignments can be scanned using the University of California, Santa Cruz's Genome Browser,; the National Center for Biotechnology Information's Map Viewer,; and the European Bioinformatics Institute's Ensembl system. An international team of scientists, led by researchers at the University of Washington in Seattle, Washington University and the Broad Institute (MIT/Harvard), is currently comparing the chimp and human genome sequences and plans to publish results of its analysis in the next several months. Chimpanzees are the most closely related species to humans. Consequently, comparative analysis of the human and chimp genomes can reveal unique types of information impossible to obtain from comparing the human genome with the genomes of other animals. Related Links Sequencing The Chimp Genome (PDF File) SpaceDaily Search SpaceDaily Subscribe To SpaceDaily Express 
Grant Renews Funding Of Research Toward Cloning Primates
Pittsburgh - Sep 01, 2003The National Institutes of Health (NIH) has awarded nearly $6.4 million to the Pittsburgh Development Center, which is affiliated with the University of Pittsburgh, to fund investigation aimed at overcoming obstacles to cloning nonhuman primates. Cloning primates is vital to generate better research models for human disease so that studies obtain more accurate results with fewer animals.
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