The Soyuz TMA-3 craft is scheduled to dock at the International Space Station (ISS) two days later, at 0711 GMT on Monday.
It is the first space mission for a European astronaut on the ISS since the disaster of the American space shuttle Columbia in February, and the presence of Spaniard Pedro Duque on the flight was seen as a boost for the European space program.
The other two astronauts are American Michael Foale and Russian Alexander Kaleri.
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